Sileo Dose In Cats

Hypertension in Cats

Sileo is packaged in an oral dosing syringe with a ring-stop mechanism on the plunger that must be 'dialed' and locked into place in order to set the correct dose for the dog. Most cats with idiopathic hypercalcemia will respond to oral alendronate, at a dose range of 10-40 mg once weekly. Like you, I start with an initial oral dose of 10 mg per week, and then gradually increase the dose based on ionized calcium concentrations monitored at 4-6 week intervals (4).

A silent disease

While hypertension can be a common problem in older cats, the condition can be difficult to diagnose.^3,4

Hypertension can affect many parts of the body before detection and is strongly associated with target organ damage^3,4:

• Eyes
• Heart and vascular system
• Brain
• Kidneys

Without treatment, this silent disease can lead to serious illness and, sometimes, death.^3,4

Most often develops as secondary hypertension to diseases such as CKD and hyperthyroidism.³

Efficacy

Proven to lower systolic blood pressure^1,10

A pilot dose determination laboratory study was conducted to evaluate the effectiveness of multiple oral doses and dose strategies of telmisartan on the reduction of systolic blood pressure (SBP) in clinically normal, healthy laboratory cats within a 14-day time period.¹¹

* Endpoint at day 14 was significant reduction from baseline compared to placebo (P < 0.0005).

† A clinically relevant reduction in group mean SBP was predefined to be ≥ 20 mmHg in the telmisartan group from baseline to Day 28. The number of cats available at Day 28 for comparison is less than at enrollment because of removal of cats for hypertension rescue or adverse reactions.

The only angiotensin receptor blocker (ARB) for first-line treatment of hypertension in cats

Because ARBs feature a unique, targeted mode of action that specifically blocks the harmful vasoconstrictive effects of the renin-angiotensin-aldosterone system (RAAS), SEMINTRA is shown to quickly lower blood pressure within 14 days‡

• Shown to be effective in cats with primary and secondary hypertension
• Proven to be safe and effective^10–13

Safety and Dosing

Flexible dosing to safely lower and maintain blood pressure in cats

• SEMINTRA offers a dose-dependent response—an initial 1.5 mg/kg (0.68 mg/lb) dose twice daily for 14 days lowers blood pressure to a healthy level quickly, followed by a 2 mg/kg (0.91 mg/lb) once daily dose to maintain control¹¹
• Dose may be reduced by 0.5 mg/kg (0.23 mg/lb) increments to a minimum of 0.5 mg/kg to optimize dosing and prevent hypotensive state

Easily given as oral liquid

— Flexible delivery of dose straight into the mouth or on top of food²

— Selection of accurate dose

— Safety shown to extend through 6 months in multiple studies^10–13

As demonstrated in a study:

— 91.2% of cat owners perfer a liquid formulation²

Mode of Action

SEMINTRA is a highly targeted treatment

Telmisartan, the active substance in SEMINTRA, is an ARB, a class of medication that modulates the RAAS by selectively blocking receptors in the effector step of the RAAS. Unlike angiotensin-converting enzyme inhibitors (ACEis), ARBs do not block the conversion of angiotensin I to angiotensin II by angiotensin-converting enzyme in the RAAS cascade, thereby also blocking the activation of some of the receptor types with beneficial effects. And, unlike a calcium channel blocker, a class of pharmaceuticals that block the influx of calcium into cardiac and smooth muscle cells through calcium channels and potentially activate the RAAS, ARBs help to manage the RAAS.

Chronic activation of the RAAS can be harmful to tissues, including the kidney.

Watch this video for more information

• Activation of RAAS can be complex, but conditions like chronic kidney disease, cardiac disease, and hyperthyroidism typically increase RAAS activity
• Chronic, excessive RAAS activation can result in systemic hypertension because it promotes salt and water retention and increases blood pressure^14,15
• ACEis reduce the conversion of circulating angiotensin I to angiotensin II, which reduces all of the effects of angiotensin II at all receptors
• ARBs have a more targeted mode of action. They bind only to the AT₁ receptor, preventing activation of this receptor by angiotensin II
• Because ARBs do not bind to AT₂ receptors, the potentially beneficial effects of angiotensin II at these receptors are preserved

Watch this video for more information

Target-specific mode of action of ARBs

IMPORTANT SAFETY INFORMATION

• SEMINTRA is for oral use in cats only.
• The most common side effects reported in field studies include vomiting, diarrhea, lethargy, dehydration, poor appetite, and weight loss. If side effects should occur, pet owners should contact their veterinarian. Click here for full prescribing information.
• SEMINTRA has not been evaluated in cats with systolic blood pressure > 200 mmHg. The safe use of SEMINTRA has not been evaluated in cats with hepatic disease, cats less than 9 months of age, or cats that are pregnant, lactating, or intended for breeding.
• The safe use of SEMINTRA with other anti-hypertensive medications has not been evaluated.
• Mild anemia or non-regenerative anemia has been reported.
• Pregnant women should avoid contact with SEMINTRA because substances that act on the renin-angiotensin-aldosterone system (RAAS), such as angiotensin receptor blockers (ARBs), can cause fetal and neonatal morbidity and death during pregnancy in humans.
• Not for human use. Keep out of reach of children. If SEMINTRA is accidentally ingested, contact a physician.
• SEMINTRA is a clear, colorless to yellowish viscous solution containing 10 mg/mL telmisartan.

References:1. SEMINTRA^® (telmisartan oral solution) Prescribing Information. Boehringer Ingelheim Vetmedica, Inc. 2018. 2. Zimmering T. Ease of use of SEMINTRA and its effects on quality of life—update on cat owner feedback ('EASY Programme') [abstract]. In: Proceedings from the 21st Federation of European Companion Animal Veterinary Associations (FECAVA); October 15–17, 2015; Barcelona, Spain. Poster. 3. Elliott J, Fletcher M, Syme HM. Idiopathic feline hypertension: epidemiologic study [abstract]. J Vet Intern Med. 2003;17:754. 4. Taylor SS, Sparkes AH, Briscoe K, et al. ISFM Consensus Guidelines on the diagnosis and management of hypertension in cats. J Feline Med Surg. 2017;19(3):288–303. 5. Maggio F, DeFrancesco TC, Atkins CE, et al. Ocular lesions associated with systemic hypertension in cats: 69 cases (1985–1998). J Am Vet Med Assoc. 2000;217:695–702. 6. Littman MP. Spontaneous systemic hypertension in 24 cats. J Vet Intern Med. 1994;8:79–86. 7. Stiles J, Polzin D, Bistner SI. The prevalence of retinopathy in cats with systemic hypertensionand chronic renal failure or hyperthyroidism. J Am Anim Hosp Assoc. 1994;30:564–572. 8. Syme HM, Barber PJ, Markwell PJ, et al. Prevalence of systolic hypertension in cats with chronic renal failure at initial evaluation. J Am Vet Med Assoc. 2002;220:1799–1804. 9. Kobayashi DL, Peterson ME, Graves TK, et al. Hypertension in cats with chronic renal failure orhyperthyroidism. J Vet Intern Med. 1990;4:58–62. 10. Coleman AE. Efficacy of oral telmisartan for the treatment of systemic hypertension in cats. In: Proceedings from the American College of Veterinary Internal Medicine; June 14–16, 2018; Seattle, WA. Abstract RRS08-E. 11. Coleman AE, Brown SA, Stark M. Evaluation of orally administered telmisartan for the reduction of indirect systolic arterial blood pressure in awake, clinically normal cats [published online ahead of print March 7, 2018]. 12. Glaus AM, Elliott J, Albrecht B, et al. Efficacy of telmisartan in hypertensive cats: results of a large European clinical trial [abstract]. J Vet Intern Med. 2018;32:577. 13. SEMINTRA^® (telmisartan oral solution) [Freedom of Information Summary]. St. Joseph, MO: Boehringer Ingelheim Vetmedica, Inc.; 2018. J Feline Med Surg. doi:10.1177/1098612X18761439. 14. Williams TL, Elliott J, Syme HM. Renin-angiotensin-aldosterone system activity in hyperthyroid cats with and without concurrent hypertension. J Vet Intern Med. 2013;27(3):522–529. 15. Syme H. Hypertension in small animal kidney disease. Vet Clin North Am Small Anim Pract. 2011;41(1):63–89.

Prednisolone for Cats: Prednisone is a corticosteroid that is given to cats for a wide variety of reasons. The dosage depends on the weight of the cat and the condition you are trying to cure. Prednisone can be found in several brand-name veterinary drugs such as Delta- Corftef, Prednis -Tab, Meticorten, Sterisol and Cortisate 20. It is also available in generic form.

Below are the types of Prednisone for cats their usage and side effects. Simply check them. If you have a cat then you must and should know how to give a cat a prednisolone and know your pet condition too. Some times there may be a side effect for this, so check our article and know more information about it.

Before going to give your cat a prednisone first see the types of prednisones that are given to a pet cat. These are type of pills that are given to a cat to cure from some diseases. This information is provided by a veterinarian so you can see below and know about it.

Contents

• 1 Types of Prednisone
• 2 Side Effects of Prednisone in Cats

Types of Prednisone

Prednisone for cats comes in the form of syrup, liquid suspension, injectable form in two concentrations and several tablets in size. Depending on the condition of the cat, the type of prednisone given will help determine the dosage amount. Pills are usually given. Injectables are preferred in cases of bacterial shock.

Anti-inflammatory

Hearts of iron 4 download for mac. Prednisone is given to cats for various anti-inflammatory conditions, including inflammatory bowel disease, allergies, severe inflammation of the skin and respiratory problems caused by swellings. According to The Pill Book Guide to Medication for Your Cat, cats are started on 1 mg of prednisone per pound that the cat weighs. It is given once or twice a day. When the cat looks better, it is given one dose every two days until the cat is cured.

Immunosuppressant

If a cat has a disease that affects the immune system where the body is attacking itself, such as cancer, then prednisone dose is different. It starts at 1 to 3 mg per pound that the cat weighs once a day, and when the cat looks better it is reduced to 1 to 2 mg every other day.

Side effects

According to Barbara Forney, VMD, cats have a greater tolerance for prednisone than dogs or horses and rarely develop bad side effects. In contact with a veterinarian or the animal venom ASPCA Control Center, if a cat on prednisone shows these side effects prednisone: excessive thirst; urinating more often than usual; sudden changes in behavior; sudden weight gain; or vomiting with diarrhea. It is normal for cats being treated with prednisone to lose some of their skin.

Schedule

Cats are able to tolerate high-dose prednisone dose for only a short time. If they are in prednisone for months, they are at risk of developing serious long-term side effects such as gastric ulcers and liver problems. In addition, because of the immunosuppressive nature of prednisone, annual vaccines may become less effective.

Sileo Dog Dose

Sileo Dose In Cats For Adoption

Side Effects of Prednisone in Cats

Prednisone is a synthetic corticosteroid. Veterinarians prescribe it to treat cats with allergies, digestive problems and other types of conditions. This medication helps the body of cats react better to many diseases. While prednisone improves the health and quality of life of many cats, it also has some side effects that are worth mentioning.

• Excessive thirst: Prednisone usually generates thirst in cats, so they will then drink excess water. That excess of water will cause the cat to have to urinate more frequently.
• Excessive hunger: Prednisone is used to stimulate appetite. This medicine can make the cat feel strong desire to eat, so you can gain weight.
• Stomach ache: Prednisone can generate discomfort in the stomach and digestive system of the cat, so you can develop a picture of diarrhea.
• Infections: Prednisone, especially in high doses, affects the immune system. Certain viruses and infections that were inactive could manifest and require treatment.
• Behavior: Prednisone can generate changes in behavior, such as sudden aggression or the attitude of hiding.
• Loss of hair: Prolonged use of prednisone will affect the cat's hair, so it will lose its shine or begin to fall.

Other Similar Articles on Cats:

• Shown to be effective in cats with primary and secondary hypertension
• Proven to be safe and effective^10–13

Safety and Dosing

Flexible dosing to safely lower and maintain blood pressure in cats

• SEMINTRA offers a dose-dependent response—an initial 1.5 mg/kg (0.68 mg/lb) dose twice daily for 14 days lowers blood pressure to a healthy level quickly, followed by a 2 mg/kg (0.91 mg/lb) once daily dose to maintain control¹¹
• Dose may be reduced by 0.5 mg/kg (0.23 mg/lb) increments to a minimum of 0.5 mg/kg to optimize dosing and prevent hypotensive state

Easily given as oral liquid

— Flexible delivery of dose straight into the mouth or on top of food²

— Selection of accurate dose

— Safety shown to extend through 6 months in multiple studies^10–13

As demonstrated in a study:

— 91.2% of cat owners perfer a liquid formulation²

Mode of Action

SEMINTRA is a highly targeted treatment

Telmisartan, the active substance in SEMINTRA, is an ARB, a class of medication that modulates the RAAS by selectively blocking receptors in the effector step of the RAAS. Unlike angiotensin-converting enzyme inhibitors (ACEis), ARBs do not block the conversion of angiotensin I to angiotensin II by angiotensin-converting enzyme in the RAAS cascade, thereby also blocking the activation of some of the receptor types with beneficial effects. And, unlike a calcium channel blocker, a class of pharmaceuticals that block the influx of calcium into cardiac and smooth muscle cells through calcium channels and potentially activate the RAAS, ARBs help to manage the RAAS.

Chronic activation of the RAAS can be harmful to tissues, including the kidney.

Watch this video for more information

• Activation of RAAS can be complex, but conditions like chronic kidney disease, cardiac disease, and hyperthyroidism typically increase RAAS activity
• Chronic, excessive RAAS activation can result in systemic hypertension because it promotes salt and water retention and increases blood pressure^14,15
• ACEis reduce the conversion of circulating angiotensin I to angiotensin II, which reduces all of the effects of angiotensin II at all receptors
• ARBs have a more targeted mode of action. They bind only to the AT₁ receptor, preventing activation of this receptor by angiotensin II
• Because ARBs do not bind to AT₂ receptors, the potentially beneficial effects of angiotensin II at these receptors are preserved

Watch this video for more information

Target-specific mode of action of ARBs

IMPORTANT SAFETY INFORMATION

• SEMINTRA is for oral use in cats only.
• The most common side effects reported in field studies include vomiting, diarrhea, lethargy, dehydration, poor appetite, and weight loss. If side effects should occur, pet owners should contact their veterinarian. Click here for full prescribing information.
• SEMINTRA has not been evaluated in cats with systolic blood pressure > 200 mmHg. The safe use of SEMINTRA has not been evaluated in cats with hepatic disease, cats less than 9 months of age, or cats that are pregnant, lactating, or intended for breeding.
• The safe use of SEMINTRA with other anti-hypertensive medications has not been evaluated.
• Mild anemia or non-regenerative anemia has been reported.
• Pregnant women should avoid contact with SEMINTRA because substances that act on the renin-angiotensin-aldosterone system (RAAS), such as angiotensin receptor blockers (ARBs), can cause fetal and neonatal morbidity and death during pregnancy in humans.
• Not for human use. Keep out of reach of children. If SEMINTRA is accidentally ingested, contact a physician.
• SEMINTRA is a clear, colorless to yellowish viscous solution containing 10 mg/mL telmisartan.

References:1. SEMINTRA^® (telmisartan oral solution) Prescribing Information. Boehringer Ingelheim Vetmedica, Inc. 2018. 2. Zimmering T. Ease of use of SEMINTRA and its effects on quality of life—update on cat owner feedback ('EASY Programme') [abstract]. In: Proceedings from the 21st Federation of European Companion Animal Veterinary Associations (FECAVA); October 15–17, 2015; Barcelona, Spain. Poster. 3. Elliott J, Fletcher M, Syme HM. Idiopathic feline hypertension: epidemiologic study [abstract]. J Vet Intern Med. 2003;17:754. 4. Taylor SS, Sparkes AH, Briscoe K, et al. ISFM Consensus Guidelines on the diagnosis and management of hypertension in cats. J Feline Med Surg. 2017;19(3):288–303. 5. Maggio F, DeFrancesco TC, Atkins CE, et al. Ocular lesions associated with systemic hypertension in cats: 69 cases (1985–1998). J Am Vet Med Assoc. 2000;217:695–702. 6. Littman MP. Spontaneous systemic hypertension in 24 cats. J Vet Intern Med. 1994;8:79–86. 7. Stiles J, Polzin D, Bistner SI. The prevalence of retinopathy in cats with systemic hypertensionand chronic renal failure or hyperthyroidism. J Am Anim Hosp Assoc. 1994;30:564–572. 8. Syme HM, Barber PJ, Markwell PJ, et al. Prevalence of systolic hypertension in cats with chronic renal failure at initial evaluation. J Am Vet Med Assoc. 2002;220:1799–1804. 9. Kobayashi DL, Peterson ME, Graves TK, et al. Hypertension in cats with chronic renal failure orhyperthyroidism. J Vet Intern Med. 1990;4:58–62. 10. Coleman AE. Efficacy of oral telmisartan for the treatment of systemic hypertension in cats. In: Proceedings from the American College of Veterinary Internal Medicine; June 14–16, 2018; Seattle, WA. Abstract RRS08-E. 11. Coleman AE, Brown SA, Stark M. Evaluation of orally administered telmisartan for the reduction of indirect systolic arterial blood pressure in awake, clinically normal cats [published online ahead of print March 7, 2018]. 12. Glaus AM, Elliott J, Albrecht B, et al. Efficacy of telmisartan in hypertensive cats: results of a large European clinical trial [abstract]. J Vet Intern Med. 2018;32:577. 13. SEMINTRA^® (telmisartan oral solution) [Freedom of Information Summary]. St. Joseph, MO: Boehringer Ingelheim Vetmedica, Inc.; 2018. J Feline Med Surg. doi:10.1177/1098612X18761439. 14. Williams TL, Elliott J, Syme HM. Renin-angiotensin-aldosterone system activity in hyperthyroid cats with and without concurrent hypertension. J Vet Intern Med. 2013;27(3):522–529. 15. Syme H. Hypertension in small animal kidney disease. Vet Clin North Am Small Anim Pract. 2011;41(1):63–89.

Prednisolone for Cats: Prednisone is a corticosteroid that is given to cats for a wide variety of reasons. The dosage depends on the weight of the cat and the condition you are trying to cure. Prednisone can be found in several brand-name veterinary drugs such as Delta- Corftef, Prednis -Tab, Meticorten, Sterisol and Cortisate 20. It is also available in generic form.

Below are the types of Prednisone for cats their usage and side effects. Simply check them. If you have a cat then you must and should know how to give a cat a prednisolone and know your pet condition too. Some times there may be a side effect for this, so check our article and know more information about it.

Before going to give your cat a prednisone first see the types of prednisones that are given to a pet cat. These are type of pills that are given to a cat to cure from some diseases. This information is provided by a veterinarian so you can see below and know about it.

Contents

• 1 Types of Prednisone
• 2 Side Effects of Prednisone in Cats

Types of Prednisone

Prednisone for cats comes in the form of syrup, liquid suspension, injectable form in two concentrations and several tablets in size. Depending on the condition of the cat, the type of prednisone given will help determine the dosage amount. Pills are usually given. Injectables are preferred in cases of bacterial shock.

Anti-inflammatory

Hearts of iron 4 download for mac. Prednisone is given to cats for various anti-inflammatory conditions, including inflammatory bowel disease, allergies, severe inflammation of the skin and respiratory problems caused by swellings. According to The Pill Book Guide to Medication for Your Cat, cats are started on 1 mg of prednisone per pound that the cat weighs. It is given once or twice a day. When the cat looks better, it is given one dose every two days until the cat is cured.

Immunosuppressant

If a cat has a disease that affects the immune system where the body is attacking itself, such as cancer, then prednisone dose is different. It starts at 1 to 3 mg per pound that the cat weighs once a day, and when the cat looks better it is reduced to 1 to 2 mg every other day.

Side effects

According to Barbara Forney, VMD, cats have a greater tolerance for prednisone than dogs or horses and rarely develop bad side effects. In contact with a veterinarian or the animal venom ASPCA Control Center, if a cat on prednisone shows these side effects prednisone: excessive thirst; urinating more often than usual; sudden changes in behavior; sudden weight gain; or vomiting with diarrhea. It is normal for cats being treated with prednisone to lose some of their skin.

Schedule

Cats are able to tolerate high-dose prednisone dose for only a short time. If they are in prednisone for months, they are at risk of developing serious long-term side effects such as gastric ulcers and liver problems. In addition, because of the immunosuppressive nature of prednisone, annual vaccines may become less effective.

Sileo Dog Dose

Sileo Dose In Cats For Adoption

Side Effects of Prednisone in Cats

Prednisone is a synthetic corticosteroid. Veterinarians prescribe it to treat cats with allergies, digestive problems and other types of conditions. This medication helps the body of cats react better to many diseases. While prednisone improves the health and quality of life of many cats, it also has some side effects that are worth mentioning.

• Excessive thirst: Prednisone usually generates thirst in cats, so they will then drink excess water. That excess of water will cause the cat to have to urinate more frequently.
• Excessive hunger: Prednisone is used to stimulate appetite. This medicine can make the cat feel strong desire to eat, so you can gain weight.
• Stomach ache: Prednisone can generate discomfort in the stomach and digestive system of the cat, so you can develop a picture of diarrhea.
• Infections: Prednisone, especially in high doses, affects the immune system. Certain viruses and infections that were inactive could manifest and require treatment.
• Behavior: Prednisone can generate changes in behavior, such as sudden aggression or the attitude of hiding.
• Loss of hair: Prolonged use of prednisone will affect the cat's hair, so it will lose its shine or begin to fall.

Other Similar Articles on Cats:

Conclusion

Hope you have simply got an idea of how to give a prednisone for cat and what dosage should be given to the cats. If you want to know more information then simply check our website Catsfud. Also share this article in the social networking sites like twitter and facebook if you like it.